study shows: Multidrug-resistant bacteria in wild rats

Kathrin Guttmann Health

A study in Vienna, in the years 2016 and 2017 was carried out, mention, that, that wild rats can not only be carriers of germs. Worryingly, that multidrug-resistant strains in them bacteria were found.

Multi-drug resistant bacteria are bacteria, which are resistant to various antibiotics.

In their study Desvars-Larrive et al investigated. 1) Desvars-Larrive Amelie, Ruppitsch Werner, Lepuschitz Sarah, Szostak Michael P, Spergser Joachim, Feßler Andrea T, Black Stefan, Monecke Stefan, Ehricht Ralf, waltz Chris, Loncaric Igor. Urban brown rats (Rattus norvegicus) as possible source of multidrug-resistant Enterobacteriaceae and meticillin-resistant Staphylococcus spp., Vienna, Austria, 2016 and 2017. Euro Surveill. 2019;24(32):pii = 1900149. https://doi.org/10.2807/1560-7917.ES.2019.24.32.1900149 62 Norway rats (Rattus Norvegicus), the most frequented places in two of rats in Vienna, Austria, were captured.

In 14,5% these rats were found multiresistant enterobacteria. This was to multidrug-resistant Escherichia coli (including ESBLA-producing), CarbapenemB-ESBL-resistant produzierende Enterobacter cloacae, largely antibiotic-resistant Enterobacter xiangfangensis from as well as numerous multi-resistant Staphylococcus strains 7 species (darunter MethicilinC-resistant S. aureaus, S. Fleuretti, S. xylosus, S. haemolyticus) be detected. These results are consistent with the prevalence of multidrug-resistant bacteria in wild Norway rats in Berlin, Where 13,6% of the tested animals had a finding 3)Guenther S, Bethe A, A Fruth, Semmler T, Ulrich RG, voters LH, et al. Frequent combination of antimicrobial multiresistance and extraintestinal pathogenicity in Escherichia coli isolates from urban rats (Rattus norvegicus) in Berlin, Germany. PLoS One. 2012;7(11):e50331. https://doi.org/10.1371/journal.pone.0050331 PMID: 23189197 . The World Health Organization published 2017 for the first time a list of antibiotic-resistant bacteria, the "represent the greatest threat to human health" 2)WHO publishes list of bacteria for which new antibiotics are urgently needed. In: website of World Health Organization (WHO). 27. February 2017, Retrieved on 2. April 2018. These include priority 1 (critical) carbapenem-resistant ESBL-producing enterobacteria, as found in the sample of Wiener brown rats. Under Priority Two (high) the isolated also in the sample Methicillin-resistant Staphylococcus aureus is out.

The present study shows, that the wildlife in urban areas Wanderratte still a significant health threat, especially as regards the spread of multi-resistant bacteria. people, take the wild Norway rats babies for hand-rearing to be, should is important to understand and point out the case of serious illness, that they may have come in contact with such germs.

A β-Lactamasen sind Enzyme, which are formed from numerous bacteria. they hydrolyze (columns) thereby preventing a common structural component of the β-lactam antibiotics and the effect of these drugs. Extended spectrum β-lactamases can a larger (expanded) Spectrum β-lactam containing antibiotics split.

B carbapenem, originally called thienamycins, sind b-Lactam-Antibiotika, which are used as drugs because of their broad spectrum antibacterial agent.

C Methicillin is an antibiotic from the group of β-lactam antibiotics.

cover photo: Janice Carr / CDC - CDC, Atlanta, USA, from de:WP, Public domain, https://commons.wikimedia.org/w/index.php?curid=716051

References   [ + ]

1. Desvars-Larrive Amelie, Ruppitsch Werner, Lepuschitz Sarah, Szostak Michael P, Spergser Joachim, Feßler Andrea T, Black Stefan, Monecke Stefan, Ehricht Ralf, waltz Chris, Loncaric Igor. Urban brown rats (Rattus norvegicus) as possible source of multidrug-resistant Enterobacteriaceae and meticillin-resistant Staphylococcus spp., Vienna, Austria, 2016 and 2017. Euro Surveill. 2019;24(32):pii = 1900149. https://doi.org/10.2807/1560-7917.ES.2019.24.32.1900149
2. WHO publishes list of bacteria for which new antibiotics are urgently needed. In: website of World Health Organization (WHO). 27. February 2017, Retrieved on 2. April 2018
3. Guenther S, Bethe A, A Fruth, Semmler T, Ulrich RG, voters LH, et al. Frequent combination of antimicrobial multiresistance and extraintestinal pathogenicity in Escherichia coli isolates from urban rats (Rattus norvegicus) in Berlin, Germany. PLoS One. 2012;7(11):e50331. https://doi.org/10.1371/journal.pone.0050331 PMID: 23189197